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Search Results for " glutathione synthetase "

3

抑制剂 & 化合物

1

化合物库

1

重组蛋白

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Cat. No.	Product Name
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；

化合物库

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

Cat. No.	Product Name	Target	Signaling Pathways
T35454	γ-Glu-Cys (ammonium salt)
	γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2
T36073	S-Acetyl-L-glutathione
	S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases ...
T60407	L-Buthionine-(S,R)-sulfoximine hydrochloride
	L-Buthionine-(S,R)-sulfoximine hydrochloride 是一种有效的、可细胞渗透的，作用快的 G-谷氨酸半胱氨酸合成酶 (γ-glutamylcysteine synthetase, γ-GCS)的不可逆抑制剂并可耗尽细胞内的谷胱甘肽水平，在黑色素瘤、乳腺癌和卵巢癌标本上的 IC50值分别为1.9 μM、8.6 μM 和 29 μM。

化合物

γ-Glu-Cys (ammonium salt)

Cat.No: T35454

S-Acetyl-L-glutathione

Cat.No: T36073

L-Buthionine-(S,R)-sulfoximine hydrochloride

Cat.No: T60407

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00979	GSH-S Protein, Human, Recombinant (His) Glutathione Synthetase,GSS,GSH-S,GSH S...	Human	E. coli
	Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...

重组蛋白

GSH-S Protein, Human, Recombinant (His)

Cat.No: TMPJ-00979

Species: Human

Expression System: E. coli

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